Genetics | Oncogenetics

Test genetico BRCA1 & BRCA2

The test that identifies predisposition to breast and ovarian cancer

Genetics | Oncogenetics

Test genetico BRCA1 & BRCA2

The test that identifies predisposition to breast and ovarian cancer

Genetics | Oncogenetics

Test genetico BRCA1 & BRCA2

The test that identifies predisposition to breast and ovarian cancer

Why take a BRCA1 and BRCA2 genetic test?

1

5-7% of breast cancers and 7-10% of ovarian cancers are hereditary and often associated with mutations in the BRCA1 and BRCA2 genes (Source: AIRC, the Italian Association for Cancer Research)

2

Women with BRCA1 or BRCA2 mutations have up to an 87% risk of developing breast cancer and up to a 40% risk of developing ovarian cancer1,2,3,4

3

Identifying individuals at risk makes it possible to:
- Implement preventive strategies, also for family members
- Initiate targeted therapies in cases of already diagnosed cancer

Why choose the BRCA1 and BRCA2 test from Next Lab Italy?

Book your BRCA1 e BRCA2 genetic test in 3 simple steps, or complete the contact form at the bottom of the page to request more information:

2

2. Provide a blood sample (home collection available!)

3

Receive your report online

Possible test results

Presence of pathogenic mutations

The test has identified mutations in the BRCA1/BRCA2 genes associated with a high risk of developing breast, ovarian, or other cancers. Not all individuals with BRCA1/2 pathogenic mutations will develop cancer, but their risk is higher than that of the general population.

Presence of mutations of uncertain clinical significance

The test may sometimes reveal mutations whose clinical significance is uncertain or unknown — meaning it is not currently possible to determine whether they are benign variants of the gene or ones that may increase cancer risk.

Absence of pathogenic mutations

The test did not identify any BRCA1/2 mutations associated with an increased risk of breast or other cancers. These individuals have a risk level comparable to that of the general population. However, a negative result does not exclude the presence of other risk factors for breast and ovarian cancer that are not detectable by the BRCA1/2 test.

The test is performed at the Pavia operational site, which implements a quality management system in accordance with ISO 9001:2015 and SIGUCert standards

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